Neuropeptide Deep Crease Serum, 1 oz.

$160.65 (15% off)FRIENDapplied$189.00
Size:1.00 oz
Offers & perks
27/mo.* suggested payments for 6-months totaling $160.65 with Macy's Card.

Product Details

  • Targeted skin refinement begins with this Perricone MD Neuropeptide Deep Crease Serum focused on improving the look of lines around the mouth, eyes, lips, and forehead. Neuropeptides and plant stem cells help support wrinkle reduction and improve the appearance of skin density for a smoother look.
  • Features

    • WHAT IT IS:
    • A highly-potent silky serum.
    • WHAT IT DOES:
    • Helps smooth the look of even the most stubborn, deep lines, wrinkles, and creases around the mouth, eyes, lips & forehead. Reduces the appearance of deep creases, marionette & lip lines.
    • INGREDIENT HIGHLIGHTS:
    • Formulated with neuropeptides, peptides
    • SKIN TYPES:
    • Suitable for all skin types
    • HOW TO USE:
    • After cleansing, massage onto face & neck using a gentle upward motion. Wait until fully absorbed & follow with your favorite Perricone MD moisturizer. Use morning and evening.
  • Shipping & Returns

    • This item qualifies for Free Shipping with minimum purchase! exclusions & details
    • Enjoy a longer window to return most of your holiday purchases. See our Extended Holiday Return Policy to see if this item qualifies.
    • California and Minnesota customers call 1-800-289-6229 for Free Shipping information.
    • For complete details, see our Shipping and Returns policies.
  • Web ID: 25409545

Ratings & Reviews

Here's what customers think
  • Many customers report visible improvements in the appearance of fine lines and deeper creases, especially around the mouth, eyes, and forehead.
  • The serum has a smooth, silky, and lightweight texture that absorbs quickly without feeling greasy or sticky.
  • Customers frequently mention that the dropper applicator is difficult to use due to the serum's thick consistency.
  • Reviewers note that the serum leaves skin feeling hydrated, soft, and plump, contributing to a more refreshed and youthful look.
  • The product generally has a mild or pleasant scent, though some customers find it too strong or dislike the fragrance.
AI-generated summary from 727 customers reviews.

4.5/5

737 star ratings, 736 reviews

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736 reviewssorted by Newest

Duffy
2 months ago
from Phoenix,AZ

Valley disappearing

Easy to use/First thing I have used that seems to actually help the deep crease lines

Recommends this product

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care2 months ago

Thank you for your wonderful feedback! We're delighted to hear this product fits seamlessly into your routine and has helped improve the look of your deep lines. Your results are exactly what we love to hear, and we're so glad you're enjoying it!

Glam-ma
2 months ago
from California

Glamma feels youthful again

Eileen always guides me in the best direction. I am not as familiar with the varied products and what they target. She is so patient to walk me thru familiarizing myself with what i should purchase.

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care2 months ago

We're so happy to hear about your positive experience with Eileen! Taking the time to understand each customer's needs and recommending the best products is what great service is all about. Thank you for recognizing her efforts, and we appreciate you sharing your feedback with us!

External reviewer
2 months ago

Product Review

I have been using this product for 3-4 months but have not seen any noticeable difference in the deep creases in my face. I still have a bottle of this serum and will continue using it in hopes of seeing a difference.

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care2 months ago

Thank you for feedback. We regret that the product did not meet your expectations. We would appreciate the opportunity to discuss this further and provide a resolution. If you wouldn't mind giving us a call at (844)334-9398 at the earliest convenience, looking forward to talking to you.

TStice
2 months ago
from Bristow Oklahoma

Great product

Im seeing instant changes in my skin. Looking younger.

Recommends this product

Customer review from Perricone MD

Response from Perricone MD

Perricone Customer Care2 months ago

Hello, we are delighted you liked this product and we thank you for sharing such valuable feedback :)

dodi
3 months ago

bad batch or huge change in formulation

consistency of water for eyelift serum- i've been using for years so i know. a major hassle to get a replacement. Not Happy

Customer review from Perricone MD

Response from Perricone MD

Gabriela3 months ago

Your satisfaction is our top priority, your feedback means a lot to us and helps us continue to improve.

Jo
3 months ago

Excellent product

My skin is noticeably better and feels so smooth. This stuff is amazing

Recommends this product

Customer review from Perricone MD

Response from Perricone MD

Ankita3 months ago

Hello, we are delighted you liked this product and we thank you for sharing such a valuable feedback :)

KellyS
3 months ago
Incentivized review

Solid Peptide for Fullness

This is a great serum. Over the few months that I used it, I noticed my skin looked fuller especially around my mouth where I have deeper smile lines. The product absorbed easily and didn’t sit on top of the skin, which I appreciated. My only gripe, and it’s a small one, is the dropper. I had a difficult time consistently picking up product each night. Overall, though, it is a beautiful product that lived up to its promises.

Customer review from Perricone MD

Wrinkles
4 months ago

Deep Crease serum

This product does what it says. It has reduced my wrinkles around my mouth and helped with the creases next to my nose. It does take time. Took 3 months of use to really see the change. I am 70.

Customer review from Perricone MD

Response from Perricone MD

Perricone MD Customer Care4 months ago

Thank you for sharing your experience! We truly appreciate your support!